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Epicrispr’s investigational gene therapy, EPI-321, is a treatment for facioscapulohumeral muscular dystrophy.
May 5, 2026
By: Patrick Lavery
Content Marketing Editor
Epicrispr Biotechnologies and Forge Biologics are beginning a strategic partnership for development and manufacturing of an adeno-associated virus (AAV) therapy. The investigational AAV gene therapy, Epicrispr’s EPI-321, intends to treat facioscapulohumeral muscular dystrophy (FSHD). According to the Muscular Dystrophy Association, FSHD most affects the muscles of the face, shoulder blades, and upper arms. EPI-321’s design silences aberrant expression of double homeobox 4, or DUX4, in skel...
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